Does dietary salt induce autoimmunity?
- PMID: 23649312
- PMCID: PMC3698635
- DOI: 10.1038/cr.2013.65
Does dietary salt induce autoimmunity?
Abstract
Two recent publications suggest that dietary salt may polarize TH17 cells and therefore increase the risk of developing autoimmune disease. Where low salt diets can readily be tested for their therapeutic effects in autoimmune disease, more work is needed to connect dietary salts with the development of immunopathology.
Comment on
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Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1.Nature. 2013 Apr 25;496(7446):513-7. doi: 10.1038/nature11984. Epub 2013 Mar 6. Nature. 2013. PMID: 23467085 Free PMC article.
References
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- Brown IJ, Tzoulaki I, Candeias V, et al. Int J Epidemiol. 2009. pp. 791–813. - PubMed
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- Croxford AL, Mair F, Becher B. Eur J Immunol. 2012. pp. 2263–2273. - PubMed
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- Ellliott P, Brown I.World Health Organization. . http://www.who.int/dietphysicalactivity/Elliot-brown-2007.pdf Accessed2013. Apr 15.
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