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Review
. 2013 Jun;41(2):67-75.
doi: 10.2967/jnmt.113.121004. Epub 2013 May 8.

Assessment of glomerular filtration rate measurement with plasma sampling: a technical review

Anthony W Murray  1 , Mark C Barnfield, Michael L Waller, Tania Telford, A Michael Peters
Affiliations
Free article
Review

Assessment of glomerular filtration rate measurement with plasma sampling: a technical review

Anthony W Murray et al. J Nucl Med Technol. 2013 Jun.
Free article

Erratum in

  • J Nucl Med Technol. 2014 Dec;42(4):12A

Abstract

This article reviews available radionuclide-based techniques for glomerular filtration rate (GFR) measurement, focusing on clinical indications for GFR measurement, ideal GFR radiopharmaceutical tracer properties, and the 2 most common tracers in clinical use. Methods for full, 1-compartment, and single-sample renal clearance characterization are discussed. GFR normalization and the role of GFR measurement in chemotherapy dosing are also considered.

Keywords: GFR measurement; GFR normalization; glomerular filtration rate; radiopharmaceutical tracer; technical review.

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