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Comment
. 2013 Apr 30;17(2):140.
doi: 10.1186/cc12610.

Delirium and cardiac surgery: progress - and more questions

Billie-Jean Martin, Rakesh C Arora
Comment

Delirium and cardiac surgery: progress - and more questions

Billie-Jean Martin et al. Crit Care. .

Abstract

Post-operative delirium is a common and dangerous complication of cardiac surgery. Many risk factors for delirium have been identified, but its pathogenesis remains largely elusive. A study by Kazmierski and colleagues investigates a more recently considered risk factor for delirium: perturbations in the hypothalamic pituitary axis and depression. This and further work may help define novel prevention and treatment strategies for delirium.

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References

    1. Martin B-J, Buth K, Arora R, Baskett R. Delirium as a predictor of sepsis in post-coronary artery bypass grafting patients: a retrospective cohort study. Crit Care. 2010;14:R171. doi: 10.1186/cc9273. - DOI - PMC - PubMed
    1. Kazmierski J, Banys A, Latek J, Bourke J, Jaszewski R. Cortisol levels and neuropsychiatric diagnosis as markers of postoperative delirium: a prospective cohort study. Crit Care. 2013;17:R38. doi: 10.1186/cc12548. - DOI - PMC - PubMed
    1. McIntosh TK, Bush HL, Yeston NS, Grasberger R, Palter M, Aun F, Egdahl RH. Beta-endorphin, cortisol and postoperative delirium: a preliminary report. Psychoneuroendocrinology. 1985;10:303–313. doi: 10.1016/0306-4530(85)90007-1. - DOI - PubMed
    1. Fuchs E, Flügge G. Stress, glucocorticoids and structural plasticity of the hippocampus. Neurosci Biobehav Rev. 1998;23:295–300. doi: 10.1016/S0149-7634(98)00031-1. - DOI - PubMed
    1. Colkesen Y, Giray S, Ozenli Y, Sezgin N, Coskun I. Relation of serum cortisol to delirium occurring after acute coronary syndromes. Am J Emerg Med. 2013;31:161–165. doi: 10.1016/j.ajem.2012.07.001. - DOI - PubMed