doi: 10.1016/j.tibtech.2013.04.006.
Epub 2013 May 9.
Not-so-incidental findings: the ACMG recommendations on the reporting of incidental findings in clinical whole genome and whole exome sequencing
Affiliations
- PMID: 23664778
- PMCID: PMC4086155
- DOI: 10.1016/j.tibtech.2013.04.006
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Not-so-incidental findings: the ACMG recommendations on the reporting of incidental findings in clinical whole genome and whole exome sequencing
Trends Biotechnol.
2013 Aug.
No abstract available
Keywords: incidental findings; returning results; whole genome sequencing.
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References
-
- Board of Directors, American College of Medical Genetics and Genomics. Points to consider in the clinical application of genomic sequencing. [last accessed April 2013];2012 Available at: http://www.acmg.net/StaticContent/PPG/Clinical_Application_of_Genomic_Se....
-
- Green RC, et al. ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. [last accessed April 2013];2013 Available at: http://www.acmg.net/docs/ACMG_Releases_Highly-Anticipated_Recommendation.... - PMC - PubMed
-
- Mand C, et al. Predictive genetic testing in minors for late-onset conditions: a chronological and analytical review of the ethical arguments. J. Med. Ethics. 2012;38:519–524. - PubMed
-
- Schoonmaker MM, et al. Factors influencing health insurers’ decisions to cover new genetic technologies. Int. J. Technol. Assess. Health Care. 2000;16:178–189. - PubMed
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