Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Jun;25(6):307-10.
doi: 10.1007/BF02544338.

Elevated levels of nonesterified fatty acids in the myocardium of alloxan diabetic rats

J Chattopadhyay  1 , E W Thompson, H H Schmid
Affiliations

Elevated levels of nonesterified fatty acids in the myocardium of alloxan diabetic rats

J Chattopadhyay et al. Lipids. 1990 Jun.

Abstract

Myocardial nonesterified fatty acids (NEFA) increase markedly within the first two days after the induction of insulin-dependent diabetes mellitus in rats by intravenous injection of alloxan. After initial variability, NEFA levels in diabetic hearts remain constant at approximately 450 nmol/g tissue (16 nmol/mumol lipid P), which is about three times higher than that in control hearts. Nonesterified linoleic acid is significantly increased in diabetic heart whereas both arachidonic and docosahexaenoic acids are decreased compared to controls.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1983 Apr;80(8):2375-9 - PubMed
    1. Biochem J. 1967 Aug;104(2):416-22 - PubMed
    1. Biochim Biophys Acta. 1976 Dec 21;451(2):363-71 - PubMed
    1. Am J Cardiol. 1981 Aug;48(2):361-5 - PubMed
    1. Am J Anat. 1988 Jul;182(3):270-82 - PubMed

Publication types

Substances

LinkOut - more resources