doi: 10.1093/jat/bkt036.
Epub 2013 May 10.
An HPLC-HR-MS-MS method for identification of anticoagulant rodenticides in blood
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- PMID: 23667199
- DOI: 10.1093/jat/bkt036
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An HPLC-HR-MS-MS method for identification of anticoagulant rodenticides in blood
J Anal Toxicol.
2013 Jul-Aug.
Abstract
This paper presents a fully validated method for the qualitative identification of bromadiolone, brodifacoum, coumachlor, coumatetralyl, difenacoum and warfarin in whole blood specimens. Samples are protein precipitated with acetonitrile, processed via solid-phase extraction and analyzed by high-performance liquid chromatography with high resolution tandem mass spectrometric detection. Limits of detection were 10 ng/mL or better for all analytes.
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