doi: 10.1002/mus.880130607.
Skeletal muscle pathology in AIDS: an autopsy study
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- PMID: 2366823
- DOI: 10.1002/mus.880130607
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Skeletal muscle pathology in AIDS: an autopsy study
Muscle Nerve.
1990 Jun.
Abstract
A survey of skeletal muscle pathology in 92 autopsied cases of AIDS revealed microscopic alterations in 64 cases. There were 40 cases of disuse atrophy, 8 of denervation atrophy, 2 of cryptococcal myositis, 1 of Mycobacterium avium intracellulare (MAI) infection and 2 of necrotizing myopathy associated with hyperkalemia. A second group of cases with changes of unknown etiology was found. These were tentatively ascribed to the direct or indirect action of HIV. This category includes 8 cases of inflammatory myopathy, 8 of necrotizing myopathy in absence of a known etiological factor, 3 of extreme atrophy and 4 of "regenerating" myopathy.
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