Head and neck cancer: causes, prevention and treatment
- PMID: 23670332
- PMCID: PMC9443822
- DOI: 10.5935/1808-8694.20130041
Head and neck cancer: causes, prevention and treatment
Abstract
Although head and neck carcinoma ranks fifth among cancer types, patient survival rates have not changed significantly over the past years.
Objective: To determine the risk factors, causes, therapies, and prevention measures for head and neck cancer.
Method: Risk factors, causes, therapies, and preventive measures for this disease were searched on databases PUBMED, MEDLINE, and SCIELO.
Results: Alcohol and tobacco are still atop risk factors. Other factors may influence the development of head and neck carcinoma. Surgery is the main treatment option, and the addition of radiotherapy following surgery is frequent for patients in the early stages of the disease. Other therapies target specific genetic molecular components connected to tumor development. Disease preventive measures include smoking cessation, limiting alcohol intake, preventing exposure to tobacco smoke and environmental carcinogenic agents, early detection of infection by HPV, maintaining oral health, good eating habits, and managing stress.
Conclusion: Additional research is needed for a more thorough understanding of the development of head and neck carcinomas and to shed light on new ways to improve therapeutic approaches and interventions.
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References
-
- Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics. CA Cancer J Clin. 2009;2009;59(4):225–249. - PubMed
-
- Haddad RI, Shin DM. Recent advances in head and neck cancer. N Eng J Med. 2008;359(11):1143–1154. - PubMed
-
- Torrente MC, Rodrigo JP, Haigentz M, Jr, Dikkers FG, Rinaldo A, Takes RP, et al. Human papillomavirus infections in laryngeal cancer. Head Neck. 2011;33(4):581–586. - PubMed
-
- Tachezy R, Klozar J, Rubenstein L, Smith E, Saláková M, Smahelová J, et al. Demographic and risk factors in patients with head and neck tumors. J Med Virol. 2009;81(5):878–887. - PubMed
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