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. 2013 Apr 26;5(4):87-93.
doi: 10.4330/wjc.v5.i4.87.

Drugs to be avoided in patients with long QT syndrome: Focus on the anaesthesiological management

Giovanni Fazio  1 , Federica Vernuccio, Giuseppe Grutta, Giuseppe Lo Re
Affiliations

Drugs to be avoided in patients with long QT syndrome: Focus on the anaesthesiological management

Giovanni Fazio et al. World J Cardiol. .

Abstract

Long QT syndrome incidence is increasing in general population. A careful pre-, peri- and post-operative management is needed for patients with this syndrome because of the risk of Torsades de Pointes and malignant arrhythmias. The available data regarding prevention of lethal Torsades de Pointes during anesthesia in patients with long QT syndrome is scant and conflicting: only case reports and small case series with different outcomes have been published. Actually, there are no definitive guidelines on pre-, peri- and post-operative anesthetic management of congenital long QT syndrome. Our review focuses on anesthetic recommendations for patients diagnosed with congenital long QT syndrome furnishing some key points for preoperative optimization, intraoperative anesthetic agents and postoperative care plan, which could be the best for patients with c-long QT syndrome who undergo surgery.

Keywords: Anesthesia; Anesthetic drugs; Long QT Syndrome; QT-prolongation; Torsades de pointes.

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