Understanding basic steps to hematopoietic stem cell transplantation evaluation
- PMID: 23675562
- PMCID: PMC3649815
Understanding basic steps to hematopoietic stem cell transplantation evaluation
Abstract
We are celebrating one millionth transplant in year 2013! With continued improvement in hematopoietic cell transplantation (HCT) outcome, the indications for HCT continue to grow. Furthermore the sources of stem cells and the number of suitable matches are expanding. At the same time, modified transplantation regimens have facilitated safer procedures despite increase in patient's age and comorbidies. In the current era, any patient indicated for HCT has a stem cell source and therefore steps to HCT and coordinated pre-transplant care is an integral part of management to improve transplant outcome. This review discusses our approach to the transplant evaluation process and this article will serve as a valuable tool for primary care physicians and referring hematologists/oncologists.
Keywords: Transplantation; evaluation; hematological malignancies; preparation.
References
-
- Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin. 2012;62:10–29. - PubMed
-
- Thomas ED. A history of bone marrow transplantation. In: Appelbaum FR, Forman SJ, Negrin RS, Blume KG, editors. Thomas’ Hematopoietic Cell Transplantation. West Sussex, UK: Wiley-Blackwell; 2009. pp. 3–7.
-
- Horowitz MM. Uses and growth of hematopoietic cell transplantation. In: Appelbaum FR, Forman SJ, Negrin RS, Blume KG, editors. Thomas’ Hematopoietic Cell Transplantation. West Sussex, UK: Wiley-Blackwell; 2009. pp. 15–21.
-
- Pasquini MC, Wang Z. Current use and outcome of hematopoietic stem cell transplantation:CIBMTR Summary Slides. 2010 at: http://www.cibmtr.org. http://www.cibmtr.org.
-
- Majhail NS, Rizzo JD, Lee SJ, Aljurf M, Atsuta Y, Bonfim C, Burns LJ, Chaudhri N, Davies S, Okamoto S, Seber A, Socie G, Szer J, Van Lint MT, Wingard JR, Tichelli A. Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation. Bone Marrow Transplant. 2012;47:337–341. - PMC - PubMed
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