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Comment
. 2013 May 15;187(10):1138-9.
doi: 10.1164/rccm.201210-1872LE.

The renin-angiotensin system in pulmonary hypertension

Nicholas W Morrell, Kurt R Stenmark
Comment

The renin-angiotensin system in pulmonary hypertension

Nicholas W Morrell et al. Am J Respir Crit Care Med. .
No abstract available

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Comment in

Comment on

  • Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.
    de Man FS, Tu L, Handoko ML, Rain S, Ruiter G, François C, Schalij I, Dorfmüller P, Simonneau G, Fadel E, Perros F, Boonstra A, Postmus PE, van der Velden J, Vonk-Noordegraaf A, Humbert M, Eddahibi S, Guignabert C. de Man FS, et al. Am J Respir Crit Care Med. 2012 Oct 15;186(8):780-9. doi: 10.1164/rccm.201203-0411OC. Epub 2012 Aug 2. Am J Respir Crit Care Med. 2012. PMID: 22859525 Free PMC article.

References

    1. de Man FS, Tu L, Handoko ML, Rain S, Ruiter G, Francois C, Schalij I, Dorfmüller P, Simonneau G, Fadel E, et al. Dysregulated renin–angiotensin–aldosterone system contributes to pulmonary arterial hypertension. Am J Respir Crit Care Med. 2012;186:780–789. - PMC - PubMed
    1. Morrell NW, Morris KG, Stenmark KR. Role of angiotensin converting enzyme and angiotensin II in development of hypoxic pulmonary hypertension. Am J Physiol. 1995;269:H1186–H1194. - PubMed
    1. Morrell NW, Atochina EN, Morris KG, Danilov SG, Stenmark KR. Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. J Clin Invest. 1995;96:1823–1833. - PMC - PubMed
    1. Orte C, Polak JM, Haworth SG, Yacoub MH, Morrell NW. Expression of pulmonary vascular angiotensin-converting enzyme in primary and secondary plexiform pulmonary hypertension. J Pathol. 2000;192:379–384. - PubMed
    1. Morrell NW, Upton PD, Kotecha S, Huntley A, Yacoub MH, Polak JM, Wharton J. Angiotensin II activates MAPK and stimulates growth of human pulmonary artery smooth msucle via AT 1 receptors. Am J Physiol. 1999;277:L440–L448. - PubMed