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. 2013 Jul;87(14):7790-2.
doi: 10.1128/JVI.01244-13. Epub 2013 May 15.

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

Raoul J de Groot  1 , Susan C Baker, Ralph S Baric, Caroline S Brown, Christian Drosten, Luis Enjuanes, Ron A M Fouchier, Monica Galiano, Alexander E Gorbalenya, Ziad A Memish, Stanley Perlman, Leo L M Poon, Eric J Snijder, Gwen M Stephens, Patrick C Y Woo, Ali M Zaki, Maria Zambon, John Ziebuhr
Affiliations

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

Raoul J de Groot et al. J Virol. 2013 Jul.
No abstract available

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Figures

Fig 1
Fig 1
Phylogenetic relationships among members of the subfamily Coronavirinae and taxonomic position of MERS-CoV. A rooted neighbor-joining tree was generated from amino acid sequence alignments of Coronaviridae-wide conserved domains in replicase polyprotein 1ab (ADRP, nsp3; Mpro, nsp5; RdRP, nsp12; Hel, nsp13; ExoN, nsp14; NendoU, nsp15; O-MT, nsp16) for MERS-CoV strain Hu/Jordan-N3/2012 (GenBank accession no. KC776174.1) and for 20 other coronaviruses, each a representative of a currently recognized coronavirus species (10); equine torovirus Berne served as the outgroup. Virus names are given with strain specifications; species and genus names are in italics as per convention. The tree shows the four main monophyletic clusters, corresponding to genera Alpha-, Beta-, Gamma-, and Deltacoronavirus (color coded) and the position of MERS-CoV. Also indicated are betacoronavirus lineages A through D (corresponding to former CoV subgroups 2A through D). Bootstrap values (1,000 replicates) are indicated at branch points. The tree is drawn to scale (scale bar, 0.2 amino acid substitutions per site).
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References

    1. Zaki A. 2012. Novel coronavirus—Saudi Arabia: human isolate. Int. Soc. Infect. Dis. ProMED-mail. http://www.promedmail.org/direct.php?id=20120920.1302733
    1. Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. 2012. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N. Engl. J. Med. 367:1814–1820 - PubMed
    1. van Boheemen S, de Graaf M, Lauber C, Bestebroer TM, Raj VS, Zaki AM, Osterhaus AD, Haagmans BL, Gorbalenya AE, Snijder EJ, Fouchier RA. 2012. Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. mBio. 3:e00473.10.1128/mBio.00473-12 - DOI - PMC - PubMed
    1. Bermingham A, Chand MA, Brown CS, Aarons E, Tong C, Langrish C, Hoschler K, Brown K, Galiano M, Myers R, Pebody RG, Green HK, Boddington NL, Gopal R, Price N, Newsholme W, Drosten C, Fouchier RA, Zambon M. 2012. Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012. Euro Surveill. 17:20290 http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20290 - PubMed
    1. European Centre for Disease Prevention and Control (ECDC) 2012. Communicable Disease Threats Report, Week 18, 29 April–5 May 2012, p 2 Severe respiratory disease of unknown origin—Jordan—outbreak in ICU. http://www.ecdc.europa.eu/en/publications/Publications/CDTR%20online%20v...