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Case Reports
. 2013;40(2):204-6.

Fertile eunuch syndrome in association with biventricular noncompaction, bicuspid aortic valve, severe aortic stenosis, and talipes equinovarus

Kazim Serhan Ozcan  1 , Damirbek Osmonov, Servet Altay, Baris Gungor, Mehmet Eren
Affiliations
Case Reports

Fertile eunuch syndrome in association with biventricular noncompaction, bicuspid aortic valve, severe aortic stenosis, and talipes equinovarus

Kazim Serhan Ozcan et al. Tex Heart Inst J. 2013.

Abstract

Noncompaction of the ventricular myocardium is a congenital cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses. In most cases, noncompaction is an isolated disease confined to the left ventricular myocardium. Fertile eunuch syndrome is a hypogonadotropic hormonal disorder in which the levels of testosterone and follicle-stimulating hormone are low. We report a case of biventricular noncompaction in association with bicuspid aortic valve and severe aortic stenosis in a 42-year-old man who was diagnosed with talipes equinovarus and fertile eunuch syndrome during childhood.

Keywords: Aortic valve/abnormalities; aortic valve, bicuspid; biventricular noncompaction; fertile eunuch syndrome; heart defects, congenital; heart ventricles/abnormalities; hypogonadism; talipes equinovarus.

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Figures

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Fig. 1 Transthoracic echocardiogram (subcostal 4-chamber view) shows marked trabeculations (arrows) in the apical segment of both left (LV) and right ventricular (RV) chambers.
See this image and copyright information in PMC

References

    1. Stollberger C, Finsterer J. Left ventricular hypertrabeculation/noncompaction. J Am Soc Echocardiogr 2004;17(1):91–100. - PubMed
    1. De Souza E, Morris JK; EUROCAT Working Group. Case-control analysis of paternal age and trisomic anomalies. Arch Dis Child 2010;95(11):893–7. - PubMed
    1. Erem C, Kocak M, Hacihasanoglu A, Yilmaz M. Blood coagulation and fibrinolysis in male patients with hypogonadotropic hypogonadism: plasma factor V and factor X activities increase in hypogonadotropic hypogonadism. J Endocrinol Invest 2008;31(6):537–41. - PubMed
    1. Jimenez-Balderas FJ, Tapia-Serrano R, Fonseca ME, Arellano J, Beltran A, Yanez P, et al. High frequency of association of rheumatic/autoimmune diseases and untreated male hypogonadism with severe testicular dysfunction. Arthritis Res 2001;3(6):362–7. - PMC - PubMed
    1. Matsumoto R, Shimizu C, Nagai S, Taniguchi S, Umetsu M, Kimura Y, et al. Cat-eye syndrome with isolated idiopathic hypogonadotropic hypogonadism. Intern Med 2005;44(10): 1069–73. - PubMed

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