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Review
. 2013 Apr;41(2):54-61.
doi: 10.3810/hp.2013.04.1026.

Carotid artery intima-media thickness and the renin-angiotensin system

Christopher T Johnson  1 , Luke P Brewster
Affiliations
Review

Carotid artery intima-media thickness and the renin-angiotensin system

Christopher T Johnson et al. Hosp Pract (1995). 2013 Apr.

Abstract

Carotid artery intima-media thickness (IMT) is a biomarker for cardiovascular disease that also predicts the risk of cardiovascular mortality. Angiotensin-converting enzyme (ACE) inhibition is a unique therapeutic modality because it both treats hypertension and improves arterial health and cardiovascular disease outcomes. Controversy exists regarding the role of ACE inhibitors and angiotensin receptor blockers (ARBs) in IMT regression. Our article provides an update on how ACE inhibitors and ARBs could play a role in decreasing IMT.

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