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. 2013 Jul 15;29(14):1834-6.
doi: 10.1093/bioinformatics/btt279. Epub 2013 May 15.

DrugMap Central: an on-line query and visualization tool to facilitate drug repositioning studies

Changhe Fu  1 , Guangxu Jin, Junfeng Gao, Rui Zhu, Efren Ballesteros-Villagrana, Stephen T C Wong
Affiliations

DrugMap Central: an on-line query and visualization tool to facilitate drug repositioning studies

Changhe Fu et al. Bioinformatics. .

Abstract

Summary: Systematic studies of drug repositioning require the integration of multi-level drug data, including basic chemical information (such as SMILES), drug targets, target-related signaling pathways, clinical trial information and Food and Drug Administration (FDA)-approval information, to predict new potential indications of existing drugs. Currently available databases, however, lack query support for multi-level drug information and thus are not designed to support drug repositioning studies. DrugMap Central (DMC), an online tool, is developed to help fill the gap. DMC enables the users to integrate, query, visualize, interrogate, and download multi-level data of known drugs or compounds quickly for drug repositioning studies all within one system.

Availability: DMC is accessible at http://r2d2drug.org/DMC.aspx.

Contact: STWong@tmhs.org.

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Figures

Fig. 1.
Fig. 1.
The search and query methods of the DMC database. (A) The multi-field search. (B) The visualization interface for the multi-level drug data
Fig. 2.
Fig. 2.
The visualization interface for drug-target-pathway information
See this image and copyright information in PMC

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