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. 2013 Jan;8(1):85-91.

Geographical distribution of leishmania species of human cutaneous leishmaniasis in fars province, southern iran

M Akhoundi  1 , H Hajjaran, A Baghaei, M Mohebali
Affiliations

Geographical distribution of leishmania species of human cutaneous leishmaniasis in fars province, southern iran

M Akhoundi et al. Iran J Parasitol. 2013 Jan.

Abstract

Background: The goal of this study was to know the identity of Leishmania species responsible of cutaneous leishmaniasis (CL) in Fars Province, southern Iran.

Methods: Five counties of Shiraz, Firouz Abad, Ghir-Karzin, Farashband and Larestan were prospected. Forty-four patients exhibiting cutaneous lesions were selected. Samples collected on skin lesions were examined both microscopically (after Giemsa staining) and molecularly (after PCR-RFLP).

Results: On the 44 examined patients, 39 exhibit Leishmania sp. by microscopical examination, all confirmed by PCR. For five patients with negative microscopical examination, PCR was positive for three of them. Among these 42 positive samples, 3 (7%) were infected by L. tropica and 39 (93%) by L. major.

Conclusions: Leishmania major is the most prevalent species in prospected area and L. tropica occurs in Shiraz and Ghir-Karzin counties.

Keywords: Human; Iran; Leishmania major; Leishmania tropica; PCR-RFLP.

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Figures

Fig. 1
Fig. 1
Sampled regions for suspected patients of cutaneous leishmaniasis in Fars province in southern Iran
Fig. 2
Fig. 2
Cut sites of BsuR1 (HaeIII) in amplified fragments of ITS-rDNA in different leishmania species (CLC DNA Workbench 5.2 software)
See this image and copyright information in PMC

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