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Randomized Controlled Trial
. 2013 May 14;8(5):e63227.
doi: 10.1371/journal.pone.0063227. Print 2013.

Selective transurethral resection of the prostate combined with transurethral incision of the bladder neck for bladder outlet obstruction in patients with small volume benign prostate hyperplasia (BPH): a prospective randomized study

Xin Li  1 , Jin-hong Pan, Qi-gui Liu, Peng He, Si-ji Song, Tao Jiang, Zhan-song Zhou
Affiliations
Randomized Controlled Trial

Selective transurethral resection of the prostate combined with transurethral incision of the bladder neck for bladder outlet obstruction in patients with small volume benign prostate hyperplasia (BPH): a prospective randomized study

Xin Li et al. PLoS One. .

Abstract

Purpose: Transurethral resection of the prostate (TURP) has a high failure rate in patients with small volume benign prostate hyperplasia (BPH) with bladder outlet obstruction (BOO). We describe and report the results of an alternative surgical method, selective transurethral resection of the prostate (STURP) in combination with transurethral incision of the bladder neck (TUIBN).

Methods: Patients were randomized to receive TURP or STRUP+TUIBN in combination with TUIBN. Maximum urinary flow rate (Qmax), voided volume, and post voiding residual volume (PVR) were assessed at baseline and at 1, 3, and 6 months after surgery. Efficacy of treatment was assessed by lower urinary tract symptoms and IPSS.

Results: Sixty three patients received STRUP+TUIBN and 61 received TURP. Surgical time, amount of prostate tissue resected, and blood loss was the same in both groups (all, p>0.05). The mean duration of follow-up was 9.02 and 8.53 months in patients receiving TURP and STRUP+TUIBN, respectively. At 6 months postoperatively, IPSS was 4.26±1.22 and 4.18±1.47 in patients receiving TURP and STRUP+TUIBN, respectively (p>0.05), and the Qmax in patients receiving STRUP+TUIBN was markedly higher than in those receiving TURP (28.28±6.46 mL/s vs. 21.59±7.14 mL/s; p<0.05). Bladder neck contracture and urinary tract infections were observed in 3 and 5 patients receiving TURP, respectively, and none in STURP.

Conclusions: STRUP+TUIBN may offer a more effective and safer alternative to TURP for small volume BPH patients.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

References

    1. Marszalek M, Ponholzer A, Pusman M, Berger I, Madersbacher S (2009) Transurethral resection of the prostate. Eur Urol Suppl 8: 504–512.
    1. Montorsi F, Moncada I (2006) Safety and tolerability of treatment for BPH. Eur Urol Suppl 5: 1004–1012.
    1. Rowland I (2007) Surgical and minimally invasive interventions for LUTS/BPH: highlights from 2006. Eur Urol Suppl 6: 701–709.
    1. Ruzić B, Trnski D, Kraus O, Tomasković I, Sorić T, et al. (2002) New modification of transurethral incision of the prostate in surgical treatment of bladder outlet obstruction: prospective study. Croat Med J 4: 610–614. - PubMed
    1. Yeni E, Unal D, Verit A, Gulum M (2002) Minimal transurethral prostatectomy plus bladder neck incision versus standard transurethral prostatectomy in patients with benign prostatic hyperplasia: a randomised prospective study. Urol Int 69: 283–286. - PubMed

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