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Review
. 2013 May 21;18(5):5891-935.
doi: 10.3390/molecules18055891.

Metabolites from Alternaria fungi and their bioactivities

Jingfeng Lou  1 , Linyun Fu, Youliang Peng, Ligang Zhou
Affiliations
Review

Metabolites from Alternaria fungi and their bioactivities

Jingfeng Lou et al. Molecules. .

Abstract

Alternaria is a cosmopolitan fungal genus widely distributing in soil and organic matter. It includes saprophytic, endophytic and pathogenic species. At least 268 metabolites from Alternaria fungi have been reported in the past few decades. They mainly include nitrogen-containing metabolites, steroids, terpenoids, pyranones, quinones, and phenolics. This review aims to briefly summarize the structurally different metabolites produced by Alternaria fungi, as well as their occurrences, biological activities and functions. Some considerations related to synthesis, biosynthesis, production and applications of the metabolites from Alternaria fungi are also discussed.

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Figures

Figure 1
Figure 1
Amines and amides isolated from Alternaria fungi.
Figure 2
Figure 2
Cyclopeptides isolated from Alternaria fungi.
Figure 3
Figure 3
Other nitrogen-containing metabolites isolated from Alternaria fungi.
Figure 4
Figure 4
Steroids isolated from Alternaria fungi.
Figure 5
Figure 5
Terpenoids isolated from Alternaria fungi.
Figure 6
Figure 6
Simple pyranones isolated from Alternaria fungi.
Figure 7
Figure 7
Monobenzopyranones isolated from Alternaria fungi.
Figure 8
Figure 8
Dibenzopyranones isolated from Alternaria fungi.
Figure 9
Figure 9
Naphthopyranones isolated from Alternaria fungi.
Figure 10
Figure 10
Anthraquinones isolated from Alternaria fungi.
Figure 11
Figure 11
Perylenequinone derivatives isolated from Alternaria fungi.
Figure 12
Figure 12
Phenolic metabolites isolated from Alternaria fungi.
Figure 13
Figure 13
Phthalides isolated from Alternaria fungi.
Figure 14
Figure 14
Miscellaneous metabolites isolated from Alternaria fungi.
Figure 15
Figure 15
Detoxification pathway of the phytoalexin brassinin (269) by the pathogen A. brassicicola [51].
Figure 16
Figure 16
Detoxification pathway of the phytotoxins destruxin B (50) and homodestruxin B (51) by the hosts Brassica napus and Sinapis alba [155,156].
See this image and copyright information in PMC

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