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Comment
. 2013 May 20;23(10):R456-9.
doi: 10.1016/j.cub.2013.04.033.

Chromatin: a tail of repression

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Chromatin: a tail of repression

Danesh Moazed. Curr Biol. .
Free article

Abstract

Genetic evidence on the role of specific histone amino acids or their posttranslational modifications in metazoan development has been lacking. A recent study reports that fruit flies carrying histone H3 lysine 27 (H3K27) mutations have the same homeotic gene expression and developmental defects as mutations in the enzyme that trimethylates H3K27.

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