Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Jun;34(2):273-82.
doi: 10.1016/j.ccm.2013.02.002. Epub 2013 Apr 8.

Human immunodeficiency virus-associated obstructive lung diseases

Matthew R Gingo  1 , Alison Morris, Kristina Crothers
Affiliations
Review

Human immunodeficiency virus-associated obstructive lung diseases

Matthew R Gingo et al. Clin Chest Med. 2013 Jun.

Abstract

In the era of effective antiretroviral therapy (ART), epidemiologic studies have found that persons infected with human immunodeficiency virus (HIV) have a higher prevalence and incidence of chronic obstructive pulmonary disease than HIV-uninfected persons. In comparison with HIV-uninfected persons and those with well-controlled HIV disease, HIV-infected persons with poor viral control or lower CD4 cell count have more airflow obstruction, a greater decline in lung function, and possibly more severe diffusing impairment. This article reviews the evidence linking HIV infection to obstructive lung disease, and discusses management issues related to the treatment of obstructive lung disease in HIV-infected patients.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Mechanisms related to obstructive lung disease in HIV-infected persons grouped by association with COPD/emphysema and association with asthma/airway hyperreactivity.
See this image and copyright information in PMC

References

    1. Gibson PG, Simpson JL. The overlap syndrome of asthma and COPD: what are its features and how important is it? Thorax. 2009;64(8):728–735. - PubMed
    1. Akinbami LJ, Moorman JE, Bailey C, et al. Trends in asthma prevalence, health care use, and mortality in the United States, 2001–2010. NCHS Data Brief. 2012;94:1–8. - PubMed
    1. Kazani S, Israel E. Update in asthma 2011. Am J Respir Crit Care Med. 2012;186(1):35–40. - PMC - PubMed
    1. Thun MJ, Carter BD, Feskanich D, et al. 50-year trends in smoking-related mortality in the United States. N Engl J Med. 2013;368(4):351–364. - PMC - PubMed
    1. Vestbo J, Hurd SS, Agusti AG, et al. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, GOLD executive summary. Am J Respir Crit Care Med. 2012 Aug 9. [Epub ahead of print] - PubMed

Publication types