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. 2013 Oct 1;132(3):630-8.
doi: 10.1016/j.drugalcdep.2013.04.016. Epub 2013 May 20.

Comorbidity of posttraumatic stress disorder with alcohol dependence among US adults: results from National Epidemiological Survey on Alcohol and Related Conditions

Carlos Blanco  1 , Yang Xu, Kathleen Brady, Gabriela Pérez-Fuentes, Mayumi Okuda, Shuai Wang
Affiliations

Comorbidity of posttraumatic stress disorder with alcohol dependence among US adults: results from National Epidemiological Survey on Alcohol and Related Conditions

Carlos Blanco et al. Drug Alcohol Depend. .

Abstract

Background: Despite the high rates of comorbidity of post-traumatic stress disorder (PTSD) and alcohol dependence (AD) in clinical and epidemiological samples, little is known about the prevalence, clinical presentation, course, risk factors and patterns of treatment-seeking of co-occurring PTSD-AD among the general population.

Methods: The sample included respondents of the Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Weighted means, frequencies and odds ratios (ORs) of sociodemographic correlates, prevalence of psychiatric disorders and rates of treatment-seeking were computed.

Results: In the general population, the lifetime prevalence of PTSD only, AD only and PTSD-AD was 4.83%, 13.66% and 1.59%, respectively. Individuals with comorbid PTSD-AD were more likely than those with PTSD or AD only to have suffered childhood adversities and had higher rates of Axis I and II disorders and suicide attempts. They also met more PTSD diagnostic criteria, had earlier onset of PTSD and were more likely to use drugs and alcohol to relieve their PTSD symptoms than those with PTSD only; they also met more AD diagnostic criteria than those with AD only and had greater disability. Individuals with PTSD-AD had higher rates of treatment seeking for AD than those with AD only, but similar rates than those with PTSD only.

Conclusion: PTSD-AD is associated with high levels of severity across a broad range of domains even compared with individuals with PTSD or AD only, yet treatment-seeking rates are very low. There is a need to improve treatment access and outcomes for individuals with PTSD-AD.

Keywords: Alcohol dependence; Comorbidity; NESARC; Post-traumatic stress disorder (PTSD); Substance use disorders.

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References

    1. Alegria A, Hasin D, Nunes E, Liu S, Davies C, Grant B, Blanco C. Comorbidity generalized anxiety disorder and substance use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J. Clin. Psychiatry. 2010;71:1187–1195. - PMC - PubMed
    1. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. 4th edition American Psychiatric Press; Washington, DC: 1994.
    1. Baca-Garcia E, Perez-Rodriguez MM, Keyes KM, Oquendo MA, Hasin DS, Grant BF, Blanco C. Suicidal ideation and suicide attempts in the United States: 1991–1992 and 2001–2002. Mol. Psychiatry. 2010;15:250–259. - PMC - PubMed
    1. Baca-Garcia E, Perez-Rodriguez MM, Keyes KM, Oquendo MA, Hasin DS, Grant BF, Blanco C. Suicidal ideation and suicide attempts among Hispanic subgroups in the United States: 1991–1992 and 2001–2002. J. Psychiatr. Res. 2011;45:512–518. - PMC - PubMed
    1. Back S, Brady K, Sonne SC, Verduin ML. Symptom improvement in co-occurring PTSD and alcohol dependence. J. Nerv. Ment. Dis. 2006;194:690–696. - PubMed

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