Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 May 22:2013:bcr2013009698.
doi: 10.1136/bcr-2013-009698.

Multidetector CT findings of calvarial eosinophilic granuloma

Affiliations
Case Reports

Multidetector CT findings of calvarial eosinophilic granuloma

Mehmet Fatih Inci et al. BMJ Case Rep. .

Abstract

Eosinophilic granuloma (EG) is a well-recognised benign form of Langerhans-cell histiocytosis. The estimated incidence of EG is 3-4 per million of the population. More patients are children and adolescents between the ages of 1 and 15 years. The value of plain films in the diagnosis of the EG is limited and the extent of the disease is better defined by multidetector CT (MDCT) scanning. MDCT scan with multiplanar and three-dimensional reconstruction image of the skull and brain clearly demonstrates bone destruction and soft-tissue involvement of the tumour. In this article we present the MDCT imaging characteristics of EG of the skull and discuss the differential diagnosis of this rare lesion with reference to recent literatures.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Axial (A), sagittal (B), coronal (C) section cranial multidetector CT scan shows an osteolytic lesion on the right parietal skull with a large epidural and subcutaneous soft tissue density mass (arrows).
Figure 2
Figure 2
Three-dimensional reconstruction of multidetector CT scan shows a significant protuberance on the right parietal scalp (A) and a large, well-defined, irregular marginated, osteolytic lesion involving the right parietal bone was detected (B) (arrows).

References

    1. Angeli SI, Alcalde J, Hoffman HT, et al. Langerhans’ cell histiocytosis of the head and neck in children. Ann Otol Rhinol Laryngol 1995;2013:173–80 - PubMed
    1. Boutsen Y, Esselinck W, Delos M, et al. Adult onset of multifocal eosinophilic granuloma of bone: a long-term follow-up with evaluation of various treatment options and spontaneous healing. Clin Rheumatol 1999;2013:69–73 - PubMed
    1. Brabencova E, Tazi A, Lorenzato M, et al. Langerhans cells in Langerhans cell granulomatosis are not actively proliferating cells. Am J Pathol 1998;2013:1143–9 - PMC - PubMed
    1. David R, Oria RA, Kumar R, et al. Radiologic features of eosinophilic granuloma of bone. AJR 1989;2013:1021–6 - PubMed
    1. Mitnick JS, Pinto RS. Computed tomography in the diagnosis of eosinophilic granuloma. J Comput Assist Tomogr 1980;2013:791–3 - PubMed

Publication types