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Comment
. 2013 Jun;62(6):1829-30.
doi: 10.2337/db13-0353.

Disrupting rhythms: diet-induced obesity impairs diurnal rhythms in metabolic tissues

Lisa Wu  1 , Akhilesh B Reddy
Affiliations
Comment

Disrupting rhythms: diet-induced obesity impairs diurnal rhythms in metabolic tissues

Lisa Wu et al. Diabetes. 2013 Jun.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Obesity is known to induce physiological changes in measures of gluconeogenesis, leptin secretion, and blood pressure and to elevate risk of cardiac incidence. In this issue, Prasai et al. (15) examine how diet-induced obesity interferes with the circadian clockwork in the liver, adipose, and cardiovascular tissues. Despite demonstrating the blunting of diurnal rhythms in the expression of clock genes and downstream effectors in adipose tissue, the broad mechanisms of how the circadian clockwork results in the dysfunction exemplified in metabolic syndrome remains a mystery.
See this image and copyright information in PMC

Comment on

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