MCM loading--an open-and-shut case?
- PMID: 23706815
- DOI: 10.1016/j.molcel.2013.05.008
MCM loading--an open-and-shut case?
Abstract
Two recent studies, from Fernández-Cid et al. (2013) (this issue of Molecular Cell) and Frigola et al. (2013), have elegantly dissected key events and interactions in the loading of the budding yeast replicative helicase MCM(2-7).
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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ATPase-dependent quality control of DNA replication origin licensing.Nature. 2013 Mar 21;495(7441):339-43. doi: 10.1038/nature11920. Epub 2013 Mar 10. Nature. 2013. PMID: 23474987 Free PMC article.
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An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.Mol Cell. 2013 May 23;50(4):577-88. doi: 10.1016/j.molcel.2013.03.026. Epub 2013 Apr 18. Mol Cell. 2013. PMID: 23603117
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