Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Mar;23(3):187-95.
doi: 10.1136/bmjqs-2012-001782. Epub 2013 May 24.

Practices to prevent venous thromboembolism: a brief review

Affiliations
Review

Practices to prevent venous thromboembolism: a brief review

Brandyn D Lau et al. BMJ Qual Saf. 2014 Mar.

Abstract

Background: Venous thromboembolism (VTE) is a common cause of preventable harm for hospitalised patients. Over the past decade, numerous intervention types have been implemented in attempts to improve the prescription of VTE prophylaxis in hospitals, with varying degrees of success. We reviewed key articles to assess the efficacy of different types of interventions to improve prescription of VTE prophylaxis for hospitalised patients.

Methods: We conducted a search of MEDLINE for key studies published between 2001 and 2012 of interventions employing education, paper based tools, computerised tools, real time audit and feedback, or combinations of intervention types to improve prescription of VTE prophylaxis for patients in hospital settings. Process outcomes of interest were prescription of any VTE prophylaxis and best practice VTE prophylaxis. Clinical outcomes of interest were any VTE and potentially preventable VTE, defined as VTE occurring in patients not prescribed appropriate prophylaxis.

Results: 16 articles were included in this review. Two studies employed education only, four implemented paper based tools, four used computerised tools, two evaluated audit and feedback strategies, and four studies used combinations of intervention types. Individual modalities result in improved prescription of VTE prophylaxis; however, the greatest and most sustained improvements were those that combined education with computerised tools.

Conclusions: Many intervention types have proven effective to different degrees in improving VTE prevention. Provider education is likely a required additional component and should be combined with other intervention types. Active mandatory tools are likely more effective than passive ones. Information technology tools that are well integrated into provider workflow, such as alerts and computerised clinical decision support, can improve best practice prophylaxis use and prevent patient harm resulting from VTE.

Keywords: Decision support, clinical; Quality improvement; Quality improvement methodologies.

PubMed Disclaimer

References

    1. Guyatt GH, Akl EA, Crowther M, et al. Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2012;141:7S–47S - PMC - PubMed
    1. Anderson FA, Jr, Zayaruzny M, Heit JA, et al. Estimated annual numbers of US acute-care hospital patients at risk for venous thromboembolism. Am J Hematol 2007;82:777–82 - PubMed
    1. US Department of Health and Human Services The surgeon general's call to action to prevent deep vein thrombosis and pulmonary embolism. 2008. http://www.surgeongeneral.gov/topics/deepvein/ (accessed 30 Aug 2011). - PubMed
    1. Cushman JG, Agarwal N, Fabian TC, et al. Practice management guidelines for the management of mild traumatic brain injury: the EAST practice management guidelines work group. J Trauma 2001;51:1016–26 - PubMed
    1. Haut ER, Lau BD, Streiff MB. New oral anticoagulants for preventing venous thromboembolism. BMJ 2012;344:e3820. - PubMed

Publication types