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Comment
. 2013 Jul;15(4):447-8.
doi: 10.1038/aja.2013.62. Epub 2013 May 27.

The ubiquitin ligase Siah2 is revealed as an accomplice of the androgen receptor in castration resistant prostate cancer

Michael R Freeman  1
Affiliations
Comment

The ubiquitin ligase Siah2 is revealed as an accomplice of the androgen receptor in castration resistant prostate cancer

Michael R Freeman. Asian J Androl. 2013 Jul.
No abstract available

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References

    1. Matsumoto T, Sakari M, Okada M, Yokoyama A, Takahashi S, et al. The androgen receptor in health and disease. Annu Rev Physiol. 2013;75:201–24. - PubMed
    1. Waltering KK, Urbanucci A, Visakorpi T. Androgen receptor (AR) aberrations in castration-resistant prostate cancer. Mol Cell Endocrinol. 2012;360:38–43. - PubMed
    1. Chymkowitch P, Le May N, Charneau P, Compe E, Egly JM. The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process. EMBO J. 2011;30:468–79. - PMC - PubMed
    1. Qi J, Nakayama K, Cardiff RD, Borowsky AD, Kaul K, et al. Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors. Cancer Cell. 2010;18:23–38. - PMC - PubMed
    1. Qi J, Tripathi M, Mishra R, Sahgal N, Fazil L, et al. The e3 ubiquitin ligase siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity. Cancer Cell. 2013;23:332–46. - PMC - PubMed

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