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Review
. 2013 May 23:2013:bcr2013009157.
doi: 10.1136/bcr-2013-009157.

Multiple solitary plasmacytoma with multifocal bone involvement. First clinical case report in a uraemic patient

Pietro Dattolo  1 , Marco Allinovi, Stefano Michelassi, Francesco Pizzarelli
Affiliations
Review

Multiple solitary plasmacytoma with multifocal bone involvement. First clinical case report in a uraemic patient

Pietro Dattolo et al. BMJ Case Rep. .

Abstract

Multiple solitary plasmacytoma (MSP) is a rare plasma cell dyscrasia, characterised by multiple lesions of neoplastic monoclonal plasma cells. It differs from multiple myeloma by the lack of hypercalcaemia, renal insufficiency, anaemia and pathological monoclonal plasmocytosis on a random bone biopsy. We present the case of an MSP described for the first time in a patient on peritoneal dialysis. There are only few cases of MSP described in literature, and we performed a review of these cases trying to systematise the topic. The increasing clinical use of CT, MRI and positron emission tomography will enhance in the future the correct diagnosis of MSP.

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Figures

Figure 1
Figure 1
Chest CT scan: solid tissue infiltrating both the ribs and the pleura.
Figure 2
Figure 2
Cervical and thoracic spine MRI scan: mass lesion substituting most of the vertebral body of D2–D3.
Figure 3
Figure 3
Chest CT scan after surgery, radiotherapy and chemotherapy: no evidence of mass lesions in vertebral body (D3), ribs and pleura.
See this image and copyright information in PMC

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References

    1. The International Myeloma Working Group Criteria for the classification monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol 2003;2013:749–57 - PubMed
    1. Kilciksiz S, Karakoyun-Celik O, Agaoglu FY, et al. A review for solitary plasmacytoma of bone and extramedullary plasmacytoma. Scic World J 2012;2013:895765 - PMC - PubMed
    1. British Committee for Standards in Haematology Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haemato 2004;2013:717–26 - PubMed
    1. Jawad MU, Scully SP. Skeletal plasmacytoma: progression of disease and impact of local treatment; an analysis of SEER database. J Hematol Oncol 2009;2013:41. - PMC - PubMed
    1. Hughes M, Soutar R, Lucraft H, et al. Guidelines on the diagnosis and management of solitary plasmacytoma of bone, extramedullary plasmacytoma and multiple solitary plasmacytomas: 2009 Update, British Committee for Standards in Haematology, London, UK, 2009

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