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Review
. 2013 Jun;44(6 Suppl 1):S41-4.
doi: 10.1161/STROKEAHA.111.000370.

Intracranial stenting: SAMMPRIS

Colin P Derdeyn  1 , David Fiorella, Michael J Lynn, Tanya N Turan, Bethany F Lane, L Scott Janis, Marc I Chimowitz
Affiliations
Review

Intracranial stenting: SAMMPRIS

Colin P Derdeyn et al. Stroke. 2013 Jun.

Abstract

The Stenting and Aggressive Medical management for the Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial established aggressive medical management as superior to angioplasty and stenting for symptomatic intracranial atherosclerotic disease. This presentation addressessome criticisms of the trial, emphasizes key knowledge gained from the study and proposes potential new directions for research in this area.

Keywords: angioplasty; clinical trial; risk factor management; stenting; stroke.

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References

    1. Chimowitz MI, Lynn MJ, Derdeyn CP, Turan TN, Fiorella D, Lane BF, et al. Stenting versus aggressive medical therapy for intracranial arterial stenosis. N Engl J Med. 2011;365:993–1003. - PMC - PubMed
    1. Alexander MJ. Intracranial stenting for intracranial atherosclerotic disease: Still much to learn. Journal of NeuroInterventional Surgery. 2012;4:85–86. - PubMed
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    1. Derdeyn CP, Fiorella D, Chimowitz M. Response from the sammpris trial principal investigators regarding inaccuracies in this editorial. Journal of NeuroInterventional Surgery. 2012 Sep 12; Epub ahead of print. - PubMed
    1. Chimowitz MI, Fiorella D, Derdeyn CP, Turan TN, Lane BF, Janis LS, et al. Response to critique of the stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis (SAMMPRIS) trial by Abou-Chebl and Steinmetz. Stroke. 2012;43:2806–2809. - PMC - PubMed

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