Targeted therapies: Tivantinib--a cytotoxic drug in MET inhibitor's clothes?
- PMID: 23712183
- DOI: 10.1038/nrclinonc.2013.86
Targeted therapies: Tivantinib--a cytotoxic drug in MET inhibitor's clothes?
Comment on
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Tivantinib (ARQ197) displays cytotoxic activity that is independent of its ability to bind MET.Clin Cancer Res. 2013 May 1;19(9):2381-92. doi: 10.1158/1078-0432.CCR-12-3459. Epub 2013 Mar 26. Clin Cancer Res. 2013. PMID: 23532890
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Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition.Cancer Res. 2013 May 15;73(10):3087-96. doi: 10.1158/0008-5472.CAN-12-3256. Epub 2013 Apr 18. Cancer Res. 2013. PMID: 23598276 Free PMC article.
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