doi: 10.1212/WNL.0b013e318294b48a.
Why our patients (and we) need basic science research
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- PMID: 23713087
- PMCID: PMC3716401
- DOI: 10.1212/WNL.0b013e318294b48a
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Why our patients (and we) need basic science research
Neurology.
.
Abstract
In times of fiscal austerity, the tendency is to seek instant, inexpensive gratification. In the case of biomedical research, this means the shortest path to practical clinical implementation. But fueling the translational pipeline with discovery depends critically on allowing the biomedical research community to follow their science where it takes them. Fiscal constraints carry with them the risk of squelching creativity and forfeiting the power of serendipity to provide the substrate for the translational engine in the future.
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References
-
- National Institutes of Health National center for advancing translational sciences. Available at: www.ncats.nih.gov/. Accessed February 3, 2013
-
- National Institutes of Health Clinical and translational science awards. Available at: www.ncats.nih.gov/research/cts/ctsa/ctsa.html. Accessed February 3, 2013
-
- National Institutes of Health Impact of NIH research. Available at: www.nih.gov/about/impact/index.html. Accessed February 3, 2013
-
- National Institutes of Health Our health. Available at: www.nih.gov/about/impact/health.html. Accessed February 3, 2013
-
- National Science Foundation Science and technology: public attitudes and understanding. In: Science and Engineering Indicators. Washington, DC: National Science Foundation; 2012:7.1–7.53
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