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. 2013 Oct;75(10):1389-92.
doi: 10.1292/jvms.13-0094. Epub 2013 May 29.

Detection of ascitic feline coronavirus RNA from cats with clinically suspected feline infectious peritonitis

Takehisa Soma  1 , Makoto Wada, Satoshi Taharaguchi, Tomoko Tajima
Affiliations

Detection of ascitic feline coronavirus RNA from cats with clinically suspected feline infectious peritonitis

Takehisa Soma et al. J Vet Med Sci. 2013 Oct.

Abstract

Ascitic feline coronavirus (FCoV) RNA was examined in 854 cats with suspected feline infectious peritonitis (FIP) by RT-PCR. The positivity was significantly higher in purebreds (62.2%) than in crossbreds (34.8%) (P<0.0001). Among purebreds, the positivities in the Norwegian forest cat (92.3%) and Scottish fold (77.6%) were significantly higher than the average of purebreds (P=0.0274 and 0.0251, respectively). The positivity was significantly higher in males (51.5%) than in females (35.7%) (P<0.0001), whereas no gender difference has generally been noted in FCoV antibody prevalence, indicating that FIP more frequently develops in males among FCoV-infected cats. Genotyping was performed for 377 gene-positive specimens. Type I (83.3%) was far more predominantly detected than type II (10.6%) (P<0.0001), similar to previous serological and genetic surveys.

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Figures

Fig. 1.
Fig. 1.
Age frequency of the ascitic feline coronavirus (FCoV) 3’-untranslated region (UTR) gene from cats with clinically suspected feline infectious peritonitis (FIP). Black and grey bars indicate the positivity of purebreds and crossbreds, respectively. *Significant differences were observed between the purebreds and crossbreds (chi-square test). *1 Less than a year of age; P=0.0001, χ2=14.6. *2 A year of age; P=0.0119, χ2=6.3.
See this image and copyright information in PMC

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