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. 2013:2013:284516.
doi: 10.1155/2013/284516.

Vitamin D Deficiency Is Prevalent in Morbidly Obese Adolescents Prior to Bariatric Surgery

Marisa Censani  1 , Emily M Stein, Elizabeth Shane, Sharon E Oberfield, Donald J McMahon, Shulamit Lerner, Ilene Fennoy
Affiliations

Vitamin D Deficiency Is Prevalent in Morbidly Obese Adolescents Prior to Bariatric Surgery

Marisa Censani et al. ISRN Obes. 2013.

Abstract

Background: Obese adults are frequently vitamin D deficient before bariatric surgery; whether similar abnormalities exist in morbidly obese adolescents is unknown.

Objective: To determine the prevalence of vitamin D deficiency in morbidly obese adolescents.

Methods: Cross-sectional study of preoperative laboratory measures from 236 adolescents evaluated for bariatric surgery.

Results: The group (N = 219 with 25-hydroxyvitamin D (25OHD) and parathyroid hormone (PTH) levels; 76 boys, 143 girls; 15.9 ± 1.2 years; 43% Caucasian, 35% Hispanic, and 15% African American) had mean BMI of 47.6 ± 8.1 kg/m2. 25OHD levels were deficient (<20 ng/mL) in 53%; 8% had severe deficiency (<10 ng/mL); only 18% of patients were replete (>30 ng/mL). 25OHD levels were inversely associated with BMI (r = -0.28, < 0.0001) and PTH levels (r = -0.24, P = 0.0003). Race was the strongest predictor of 25OHD (P < 0.002); 82% of African Americans, 59% of Hispanics, and 37% of Caucasians were deficient. African American race, BMI, and PTH explained 21% of the variance in 25OHD (P < 0.0001).

Conclusions: Most adolescents presenting for bariatric surgery have suboptimal vitamin D levels, with African Americans and those with higher BMIs at greatest risk for vitamin D deficiency. All morbidly obese adolescents should be screened for vitamin D deficiency before bariatric procedures.

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Figures

Figure 1
Figure 1
The distribution of 25-hydroxyvitamin D (25OHD) serum concentrations in 219 morbidly obese adolescents; shaded area indicates 25OHD level below 20 ng/mL.
Figure 2
Figure 2
The association (Spearman correlation coefficient (r)) between 25-hydroxyvitamin D (25OHD) concentration and body mass index (BMI).
Figure 3
Figure 3
The association (Spearman correlation coefficient (r)) between parathyroid hormone (PTH) levels and 25-hydroxyvitamin D (25OHD) concentration.
Figure 4
Figure 4
Prevalence of 25-hydroxyvitamin D deficiency (25OHD < 20 ng/mL) according to race and body mass index (BMI).
See this image and copyright information in PMC

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