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Comment
. 2013 Jun;15(6):565-7.
doi: 10.1038/ncb2778.

Preventing lysosomal fat indigestion

Ana Maria Cuervo
Comment

Preventing lysosomal fat indigestion

Ana Maria Cuervo. Nat Cell Biol. 2013 Jun.

Abstract

Autophagy contributes to lipid catabolism through direct mobilization and breakdown of cellular lipid stores. Two recent studies reveal the regulatory mechanisms activated by cells during starvation to ensure that the cellular compartments involved in autophagic lipid catabolism are ready to receive, process and use these lipids. The regulators represent attractive therapeutic targets to help fight lipid-excess-associated diseases.

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References

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