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Comment
. 2013 Jun;144(6):640-2.
doi: 10.14219/jada.archive.2013.0175.

Amoxicillin/metronidazole therapy may improve the effectiveness of scaling and root planing in patients with periodontitis

L Virginia Powell  1
Affiliations
Comment

Amoxicillin/metronidazole therapy may improve the effectiveness of scaling and root planing in patients with periodontitis

L Virginia Powell. J Am Dent Assoc. 2013 Jun.

Abstract

SYSTEMATIC REVIEW CONCLUSION: Preliminary evidence suggests scaling and root planing (SRP) in combination with amoxicillin (AMX)/metronidazole (MET)(SRP + AMX/MET) therapy may be more effective in treating chronic periodontitis(CP) than is SRP alone. CRITICAL SUMMARY ASSESSMENT: Preliminary evidence from a meta-analysis of four randomized clinical trials (RCTs) seems to support the effectiveness of systemic AMX/MET therapy as an adjunct to SRP alone in treating CP, although safety data are incomplete. EVIDENCE QUALITY RATING: Limited.

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