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. 2012 Jun;28(2):77-81.
doi: 10.1007/s12288-011-0107-x. Epub 2011 Sep 21.

Prevalence and characterization of thrombocytopenia in pregnancy in Indian women

Singh Nisha  1 , Dhakad Amita, Singh Uma, A K Tripathi, Sankhwar Pushplata
Affiliations

Prevalence and characterization of thrombocytopenia in pregnancy in Indian women

Singh Nisha et al. Indian J Hematol Blood Transfus. 2012 Jun.

Abstract

To find the prevalence and causes of thrombocytopenia during pregnancy. An analytical prospective observational study was conducted in Department of Obstetrics & Gynecology, CSMMU, Lucknow. 1079 antenatal women screened for thrombocytopenia and investigated for cause and management strategies and fetomaternal outcome were recorded. Prevalence of thrombocytopenia was 8.8%. Gestational thrombocytopenia was seen in 64.2%, obstetric in 22.1% and medical in 13.68% cases. Mean platelet count in controls was lower with a significant fall (P < 0.001) in the platelet count as pregnancy advanced. Hypertensive and hepatic disorders were the most common obstetric causes of thrombocytopenia. Mode of delivery was not affected by thrombocytopenia. Maternal morbidity and mortality was seen only in medical and obstetric thrombocytopenia. The low platelet counts and declining trend with increasing gestational age predispose Indian women to risk of thrombocytopenia and a routine platelet count is suggested.

Keywords: Blood Transfusion Medicine; DIC; Gestational thrombocytopenia; Hematology; Human Genetics; Medical thrombocytopenia; Medicine & Public Health; Obstetric thrombocytopenia; Oncology; Platelet count; Pregnancy with ITP.

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Figures

Fig. 1
Fig. 1
Change in platelet count with increasing period of gestation in controls
Fig. 2
Fig. 2
Comparision of treatment used in different types of thrombocytopenia in pregnancy
See this image and copyright information in PMC

References

    1. Shehata N, Burrows R, Kelton JG. Gestational thrombocytopenia. Clin Obst Gynaecol. 1999;42(2):327–334. doi: 10.1097/00003081-199906000-00017. - DOI - PubMed
    1. Burrows RF, Kelton JG. Thrombocytopenia at delivery (a prospective survey of 6,715 deliveries) Am J Obstet Gynaecol. 1990;162:731–734. - PubMed
    1. Sullivan CA, Martin JN., Jr Management of the obstetric patients with thrombocytopenia. Clin Obstet Gynecol. 1995;38:521–534. doi: 10.1097/00003081-199509000-00011. - DOI - PubMed
    1. Magann EF, Martin JN. Twelve steps to optical management of HELLP syndrome. Mississippi & Tennessee classification systems for HELLP syndrome. Clin Obstet Gynecol. 1999;42(3):532–550. doi: 10.1097/00003081-199909000-00009. - DOI - PubMed
    1. Sainio S, Kekomaki R, Rikonen S, Teramo K. Maternal thrombocytopenia at term: a population-based study. Acta Obstetr Gynecol Scand. 2000;79(9):744–749. doi: 10.1034/j.1600-0412.2000.079009744.x. - DOI - PubMed

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