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Case Reports
. 2013 Jul;132(1):161-5.
doi: 10.1542/peds.2012-3643. Epub 2013 Jun 3.

Trisomy 18 and complex congenital heart disease: seeking the threshold benefit

Renee D Boss  1 , Kathryn W Holmes, Janyne Althaus, Cynda H Rushton, Hunter McNee, Theresa McNee
Affiliations
Case Reports

Trisomy 18 and complex congenital heart disease: seeking the threshold benefit

Renee D Boss et al. Pediatrics. 2013 Jul.

Abstract

A prenatal diagnosis of ductal-dependent, complex congenital heart disease was made in a fetus with trisomy 18. The parents requested that the genetic diagnosis be excluded from all medical and surgical decision-making and that all life-prolonging therapies be made available to their infant. There was conflict among the medical team about what threshold of neonatal benefit could outweigh maternal and neonatal treatment burdens. A prenatal ethics consultation was requested.

Keywords: cardiac surgery; decision-making; ethics; trisomy 18.

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