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Case Reports
. 2013 Jun;29(6):756-7.
doi: 10.1097/PEC.0b013e318294f558.

Chronic valproic acid intoxication

Dror Weiner  1 , Vered Nir, Adi Klein-Kremer, Eiass Kassem
Affiliations
Case Reports

Chronic valproic acid intoxication

Dror Weiner et al. Pediatr Emerg Care. 2013 Jun.

Abstract

Valproic acid intoxication may be associated with cerebral, cardiovascular, respiratory, gastrointestinal, and hematologic complications. We report a case of a 7-year-old girl, epilepsy-treated chronically with valproic acid, sulthiame, and clonazepam, who presented to the emergency room because of a global deterioration during the preceding 2 months, including poorer feeding and worsened general responsiveness. The girl was later diagnosed to have chronic valproic acid intoxication.

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