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. 2012 Jan 26:2012:482802.
doi: 10.5402/2012/482802. Print 2012.

The Association between Alcohol Dependence and Depression before and after Treatment for Alcohol Dependence

Mary W Kuria  1 , David M Ndetei, Isodore S Obot, Lincoln I Khasakhala, Betty M Bagaka, Margaret N Mbugua, Judy Kamau
Affiliations

The Association between Alcohol Dependence and Depression before and after Treatment for Alcohol Dependence

Mary W Kuria et al. ISRN Psychiatry. .

Abstract

The presence of depression in alcohol-dependent persons is likely to influence treatment process and outcomes. Identification of depression is important though not every depressed alcohol-dependent person requires treatment with antidepressants. Understanding the association between depression and alcohol dependence is essential for proper management of alcohol dependence. Objectives. To determine the prevalence of depression among alcohol-dependent persons before and after alcohol detoxification and rehabilitation. Design. Clinical trial with pre-/postmeasurements. Method. The CIDI and WHO-ASSIST were administered to 188 alcohol-dependent persons at intake and after six months. A researcher-designed sociodemographic questionnaire was also administered at intake. Results. The prevalence of depression among alcohol-dependent persons is high (63.8%) with a significant association between depression and the mean AUDIT score. At posttest, depressed participants had a statistically significant craving for alcohol. Conclusion. Alcohol dependence is associated with major depression.

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References

    1. Spaner D, Bland RC, Newman SC. Major depressive disorder. Acta Psychiatrica Scandinavica, Supplement. 1994;89(376):7–15. - PubMed
    1. Grant BF, Harford TC. Co morbidity between DSM-IV alcohol use disorders and major depression: results of a national survey. Drug and Alcohol Dependence. 1995;39(3):197–206. - PubMed
    1. Ross HE. DSM-III-R alcohol abuse and dependence and psychiatric co morbidity in ontario: results from the mental health supplement to the Ontario Health Survey. Drug and Alcohol Dependence. 1995;39(2):111–128. - PubMed
    1. Kessler RC, Crum RM, Warner LA, Nelson CB, Schulenberg J, Anthony JC. Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the national co morbidity survey. Archives of General Psychiatry. 1997;54(4):313–321. - PubMed
    1. Hasin DS, Grant BF. Major depression in 6050 former drinkers: association with past alcohol dependence. Archives of General Psychiatry. 2002;59(9):794–800. - PubMed

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