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Case Reports
. 2013 Mar-Apr;88(2):290-2.
doi: 10.1590/S0365-05962013000200023.

Polarized dermoscopy of mammary Paget disease

Giselly Silva Neto de Crignis  1 , Luciana de Abreu, Alice Mota Buçard, Carlos Baptista Barcaui
Affiliations
Case Reports

Polarized dermoscopy of mammary Paget disease

Giselly Silva Neto de Crignis et al. An Bras Dermatol. 2013 Mar-Apr.

Abstract
in English, Portuguese

Mammary Paget's disease is a rare intraepithelial adenocarcinoma, located on the nipple/areola complex, highly associated with breast cancer. Although the international literature emphasizes the dermatoscopic pattern of mammary Paget's disease pigmented variant, the authors describe the dermoscopic findings of classical Paget's disease and demonstrate the presence of chrysalis-like structures, criteria recently described in the literature and not yet reported in Paget's disease.

Doença de Paget mamária é considerada um adenocarcinoma intra-epitelial raro, localizado no complexo mamilo-aréola,com alta associação ao câncer de mama. Apesar da literatura mundial realçar o padrão dermatoscópico da doença de Paget mamária variante pigmentada os autores descrevem os achados dermatoscópicos da doença de Paget clássica realçando a presença das estruturas crisálida-símiles,critério recentemente descrito na literatura mundial e ainda não relatado na Doença de Paget.

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Conflict of interest statement

Conflict of interest: None

Figures

FIGURE 1
FIGURE 1
A. Clinical appearance of lesion with radical mastectomy scar on the right and change in morphology and pigmentation of the left nipple and areola; B. In more detail, lesion shows erythematous plaque on the left areolar region, with pinkish- brown color associated with centrifugal growth and retraction of the left nipple; C. Histopathological sections of mammary Paget's disease: aggregates of atypical cells in the epidermis, with large hyperchromatic nuclei and abundant cytoplasm (HE-200x); D. Melanin granules in the cytoplasm of tumor cells (PAS- 200X)
FIGURE 2
FIGURE 2
Dermatoscopic appearance of lesion. On dermoscopy the lighter portion corresponded to a whitish-pink area of the left nipple and areola, whereas the darker portion was characterized as follows: A. Light brown diffuse pigmentation and B. Irregular black dots and small blue-gray structures (peppering) irregularly distributed; C. Irregular linear vessels and D. Under polarized light, the presence of bright white streaks structures called chrysalis-like structures; note the parallel arrangement of these structures
See this image and copyright information in PMC

References

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