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Case Reports
. 2013 Mar-Apr;88(2):279-82.
doi: 10.1590/S0365-05962013000200020.

Marshall's syndrome

Elisa Fontenelle  1 , Ana Paula Moura de Almeida, Gabriela Maria Assis de Almeida Souza
Affiliations
Case Reports

Marshall's syndrome

Elisa Fontenelle et al. An Bras Dermatol. 2013 Mar-Apr.

Abstract
in English, Portuguese

Marshall's syndrome is a form of acquired cutis laxa without systemic involvement, which is preceded by an inflammatory dermatitis with a neutrophilic component. We report a case of a 6-year-old boy with clinical and histopathological features of this syndrome. The etiology remains unknown and there is no definitive treatment.

Síndrome de Marshall é uma forma de cutis laxa adquirida, sem envolvimento sistêmico, que é precedida por uma dermatite inflamatória com componente neutrofílico. Relatamos o caso de um menino de 6 anos de idade com as características clínicas e histopatológicas desta síndrome. A etiologia desta doença permanece desconhecida e ainda não existe um tratamento definitivo.

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Conflict of interest statement

Conflict of interest: None

Figures

FIGURE 1
FIGURE 1
Clinic - Acute phase. Indurated well-circumscribed erythematous plaques on the back
FIGURE 2
FIGURE 2
Acute phase: Infiltrated erythematous and edematous plaques on the face, arm and chest
FIGURE 3
FIGURE 3
Histopathology - Acute phase. Hematoxylin-eosin 400X - Dense neutrophilic dermal infiltrate with edema of the dermal papillae
FIGURE 4
FIGURE 4
Clinic - Chronic phase: Atrophic, wrinkled areas on the back
FIGURE 5
FIGURE 5
Histopathology - Chronic phase. Acid orcein staining (1000 X) - with a decrease in the number of elastic fibers in the reticular dermis. The existing fibers are shortned and fragmented
See this image and copyright information in PMC

References

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    1. Machet MC, Machet L, Vaillant L, Estève E, de Muret A, Arbeille A, et al. Cutis laxa: a manifestation of generalized elastolysis. Arch Dermatol. 1965;92:373–385. - PubMed

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