[The effect of amino acids on the excitability of identified autoactive giant neurons of Achatina fulica Férussac]
[Article in
French]
- PMID: 2374
Item in Clipboard
[The effect of amino acids on the excitability of identified autoactive giant neurons of Achatina fulica Férussac]
[Article in
French]
C R Seances Soc Biol Fil.
1975.
Abstract
Effects of the following amino acids were examined on the electrical activity of the two giant neurones (PON and TAN) identified in the subesophageal ganglia of Achatina fulica Férussac : L-Asp, L-Thr, L-Ser, L-Glu, L-Pro, Gly, L-alpha-Ala, beta-Ala, L-cysteine, L-cystine, L-Val, L-Met, L-Ileu, L-Leu, L-Tyr, L-Phe, L-Lys, L-His, L-Arg, L-Cit, L-Try, GABA and GABOB. Among these substances, we observed an inhibitory effect of GABA and GABOB on the TAN excitability. GABA showed stronger effect on the TAN than GABOB. This effect of GABA was due to producing hyperpolarization on the TAN membrane. GABA showed a slight excitatory effect on the PON. The effect of GABOB on the PON was very weak and unstable.
Similar articles
-
[Effect of oligopeptides containing L-Phe, L-Tyr, L-Trp, L-His or L-Met on the excitability of the 2 giant neurons of the African giant snail (Achatina fulica Ferussac)].C R Seances Soc Biol Fil. 1979;173(5):989-99. C R Seances Soc Biol Fil. 1979. PMID: 161198 French.
-
Identifiable Achatina giant neurones: their localizations in ganglia, axonal pathways and pharmacological features.Gen Pharmacol. 1996 Jan;27(1):3-32. doi: 10.1016/0306-3623(95)00113-1. Gen Pharmacol. 1996. PMID: 8742492 Review.
-
Achatin-I, an excitatory neurotransmitter having a D-phenylalanine residue of Achatina giant neurones.Acta Biol Hung. 1992;43(1-4):147-58. Acta Biol Hung. 1992. PMID: 1363711
-
Inhibitory effects of aromatic oligopeptides on the excitability of identifiable giant neurones of an African giant snail (Achatina fulica Férussac).Arch Int Pharmacodyn Ther. 1979 Jan;237(1):149-68. Arch Int Pharmacodyn Ther. 1979. PMID: 485679
-
Isolation of achatin-I, a neuroactive tetrapeptide having a D-phenylalanine residue, from Achatina ganglia, and its effects on Achatina giant neurones.Comp Biochem Physiol C Comp Pharmacol Toxicol. 1991;98(1):97-103. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1991. PMID: 1673921 Review.
Cited by
-
Effects of some oligopeptides, consisting of aromatic amino acids, on the excitability of an identifiable giant neurone of an African giant snail (Achatina fulica Férussac).Experientia. 1977 Oct 15;33(10):1348-50. doi: 10.1007/BF01920174. Experientia. 1977. PMID: 908410
-
Current(I)-voltage(V) relationships of the neuromembrane of an identifiable giant neurone of an African giant snail (Achatina fulica Férussac) in the presence of an inhibitory tripeptide, L-Lys-L-Phe-L-Tyr.Experientia. 1978 Aug 15;34(8):1052-3. doi: 10.1007/BF01915342. Experientia. 1978. PMID: 700024
-
Inhibitory tripeptide, Lys-Phe-Tyr, as a fragment of physalaemin.Experientia. 1977 Jul 15;33(7):938-9. doi: 10.1007/BF01951293. Experientia. 1977. PMID: 891782 No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Miscellaneous