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Case Reports
. 2013 Jan;7(1):1-4.

Two cases of complete hydatidiform mole and coexistent live fetus

Antonella Vimercati  1 , Alessandra Caterina de Gennaro, Isabella Cobuzzi, Silvana Grasso, Marinella Abruzzese, Fabiana Divina Fascilla, Gennaro Cormio, Luigi Selvaggi
Affiliations
Case Reports

Two cases of complete hydatidiform mole and coexistent live fetus

Antonella Vimercati et al. J Prenat Med. 2013 Jan.

Abstract

The aim of this study was to report the clinical features, management, and outcome of complete hydatidiform mole with a coexisting viable fetus. Two cases are reported. In both cases ultrasound examination demonstrated a normally growing live fetus alongside a normal placenta and an additional intrauterine echogenic mass with features of hydatidiform mole. The hCG levels were significantly increased and fetal karyotypes were normal. A cesarean section performed at 28 weeks' gestation in the first case and at 26 weeks' gestation in the second one resulted in the delivery of live normal infant and two adjoining placentas in both cases. Microscopic examination of the abnormal placentas confirmed complete hydatidiform mole. The babies did well and serial maternal serum hCG levels showed a declining trend and were undetectable by a few months after delivery. Continuation of a twin pregnancy with complete hydatidiform mole (CHMF) is an acceptable option. There is, although, an increased risk of developing maternal and fetal complications. Close surveillance of an ongoing pregnancy is compulsory to detect potential early signs of complications.

Keywords: complete hydatidiform mole; gestational trophoblastic disease; twin pregnancy.

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Figures

Figure 1
Figure 1
A, B. Ultrasound scan of normal (superior) and molar (inferior) placenta (A); an enlarged view of molar placenta (B).
Figure 2
Figure 2
Macroscopic appearance of normal placenta (right) and hydatidiform mole (left).
Figure 3
Figure 3
A–C. Ultrasound scan of normal (superior) and molar (inferior) placenta (A–B); an enlarged view of molar placenta (C).
See this image and copyright information in PMC

References

    1. Dolapcioglu K, Gungoren A, Hakverdi S, Hakverdi AU, Egilmez E. Twin pregnancy with a complete hydatidiform mole and co-existent live fetus: two case reports and review of the literature. Arch Gynecol Obstet. 2009;279:431–436. - PubMed
    1. Moini A, Riazi K. Molar pregnancy with a coexisting fetus progressing to a viable infant. Int J Gynecol Obstet. 2003;82:63–64. - PubMed
    1. Vaisbuch E, Ben-Arie A, Dgani R, Perlman S, Sokolovsky N, Hagay Z. Twin pregnancy consisting of a complete hydatidiform mole and co-existent fetus: report of two cases and review of literature. Gynecol Oncol. 2005;98:19–23. - PubMed
    1. Bruchim I, Kidron D, Amiel A, Altaras M, Fejgin MD. Complete hydatidiform mole and a coexistent viable fetus: report to two cases and review of the literature. Gynecol Oncol. 2000;77:197–202. - PubMed
    1. Montes-de-Oca-Valero F, Macara L, Shaker A. Twin pregnancy with a complete mole and co-existing fetus following in vitro fertilization. Hum Reprod. 1999;14:2905–2907. - PubMed

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