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. 2013 May;64(5):402-6.
doi: 10.4097/kjae.2013.64.5.402. Epub 2013 May 24.

The prevention and handling of the missing data

Affiliations

The prevention and handling of the missing data

Hyun Kang. Korean J Anesthesiol. 2013 May.

Abstract

Even in a well-designed and controlled study, missing data occurs in almost all research. Missing data can reduce the statistical power of a study and can produce biased estimates, leading to invalid conclusions. This manuscript reviews the problems and types of missing data, along with the techniques for handling missing data. The mechanisms by which missing data occurs are illustrated, and the methods for handling the missing data are discussed. The paper concludes with recommendations for the handling of missing data.

Keywords: Expectation-Maximization; Imputation; Missing data; Sensitivity analysis.

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