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. 2013 Sep;11(9):1773-5.
doi: 10.1111/jth.12310.

Hypoxia, such as encountered at high altitude, promotes deep vein thrombosis in mice

A Brill  1 , G L Suidan, D D Wagner
Affiliations

Hypoxia, such as encountered at high altitude, promotes deep vein thrombosis in mice

A Brill et al. J Thromb Haemost. 2013 Sep.
No abstract available

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Conflict of interest statement

Disclosure of Conflicts of Interest: The authors state that they have no conflict of interest.

Figures

Figure
Figure
Hypoxia/Reoxygenation (H/R) promotes DVT. Mice subjected to H/R or normoxia followed by 1 h of IVC stenosis were euthanized and thrombi examined. Thrombus weight and length are shown in WT (normoxic), n=8; WT (H/R), n=15; WT (H/R + GPG-290), n=6; TgGP1bα/IL4R, n=9 and VWF−/− mice, n=4 (A–D). Onset and rate of coagulation were measured in WT mice exposed to normoxia (n=6) or H/R (n=5) (E, F).
See this image and copyright information in PMC

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