Chromatin meets its organizers
- PMID: 23746835
- DOI: 10.1016/j.cell.2013.05.030
Chromatin meets its organizers
Abstract
Chromatin organization and gene-gene interactions are critical components of carrying out developmental programs. Phillips-Cremins et al. identify a series of unexpected architectural proteins that work in a combinatorial manner to functionally organize chromatin in a cell-type-specific manner at the submegabase-length scale.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Architectural protein subclasses shape 3D organization of genomes during lineage commitment.Cell. 2013 Jun 6;153(6):1281-95. doi: 10.1016/j.cell.2013.04.053. Epub 2013 May 23. Cell. 2013. PMID: 23706625 Free PMC article.
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