Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2013 Jul;17(7):309-10.
doi: 10.1016/j.tics.2013.05.001. Epub 2013 Jun 5.

A brain signature for acute pain

Affiliations
Comment

A brain signature for acute pain

A Vania Apkarian. Trends Cogn Sci. 2013 Jul.

Abstract

Wager and colleagues developed a functional MRI-based spatial and magnitude pattern for perception of acute pain, which seems to generalize across many task conditions and subjects. This is a strong demonstration of the existence of a pain signature and raises important questions regarding what pain and perception are.

PubMed Disclaimer

Comment on

References

    1. Head H, Holmes G. Sensory disturbances from cerebral lesions. Brain. 1911;34:102–254.
    1. Penfield W, Boldrey E. Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain. 1937;60:389–443.
    1. Apkarian AV, et al. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain. 2005;9:463–484. - PubMed
    1. Yarkoni T, et al. Large-scale automated synthesis of human functional neuroimaging data. Nat Methods. 2011;8:665–670. - PMC - PubMed
    1. Garcia-Larrea L. Insights gained into pain processing from patients with focal brain lesions. Neurosci Lett. 2012;520:188–191. - PubMed