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Comment
. 2013 Jun 4;17(6):809-811.
doi: 10.1016/j.cmet.2013.05.014.

Metformin, microbes, and aging

Gilles Storelli  1 , Mélisandre Téfit  1 , François Leulier  2
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Free article
Comment

Metformin, microbes, and aging

Gilles Storelli et al. Cell Metab. .
Free article

Abstract

The mechanisms underlying the biological activity of metformin, a widely prescribed drug to treat type 2 diabetes, remain elusive. In a recent issue of Cell, Cabreiro et al. report that in C. elegans, metformin indirectly impacts lifespan by altering the methionine metabolism of its microbial partner E. coli (Cabreiro et al., 2013).

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