SPECT-CT for characterization of extraosseous uptake of 99mTc-methylene diphosphonate on bone scintigraphy
- PMID: 23748034
- DOI: 10.5152/dir.2013.054
SPECT-CT for characterization of extraosseous uptake of 99mTc-methylene diphosphonate on bone scintigraphy
Abstract
Bone scintigraphy is a sensitive and popular method for imaging a wide array of benign or malignant skeletal abnormalities. However, the uptake of tracers used for bone scintigraphy may be observed in various extraosseous sites, thereby limiting its specificity. It is difficult to correctly localize such sites of uptake on planar bone scintigraphy alone. The addition of hybrid single-photon emission computed tomography-computed tomography (SPECT-CT) under such circumstances is very useful. The present essay illustrates the commonly encountered extraosseous uptake of 99mTc-methylene diphosphonate (MDP) and the usefulness of hybrid SPECT-CT in clarifying 99mTc-MDP uptake.
Similar articles
-
Extraosseous Findings on Bone Scintigraphy Using Fusion SPECT/CT and Correlative Imaging.AJR Am J Roentgenol. 2015 Jul;205(1):160-72. doi: 10.2214/AJR.14.13914. AJR Am J Roentgenol. 2015. PMID: 26102395
-
Diagnostic value of 99mTc-MDP SPECT/spiral CT combined with three-phase bone scintigraphy in assessing suspected bone tumors in patients with no malignant history.Nucl Med Commun. 2015 Jul;36(7):686-94. doi: 10.1097/MNM.0000000000000299. Nucl Med Commun. 2015. PMID: 25757199
-
Accurate characterization of 99mTc-MDP uptake in extraosseous neoplasm mimicking bone metastasis on whole-body bone scan: contribution of SPECT/CT.BMC Med Imaging. 2019 May 30;19(1):44. doi: 10.1186/s12880-019-0345-1. BMC Med Imaging. 2019. PMID: 31146746 Free PMC article.
-
Review of Extraskeletal Activity on Tc-99m Methylene Diphosphonate Bone Scintigraphy and Value of Cross-Sectional and SPECT-CT Imaging Correlation.Curr Probl Diagn Radiol. 2018 Sep;47(5):324-332. doi: 10.1067/j.cpradiol.2017.07.009. Epub 2017 Jul 31. Curr Probl Diagn Radiol. 2018. PMID: 28844319 Review.
-
Use of SPECT/CT with 99mTc-MDP Bone Scintigraphy to Diagnose Symptomatic Os Acromiale.J Nucl Med Technol. 2015 Sep;43(3):236-7. doi: 10.2967/jnmt.114.150102. Epub 2015 Feb 5. J Nucl Med Technol. 2015. PMID: 25655344 Review.
Cited by
-
Predictive value of single photon emission computerized tomography and computerized tomography in osteonecrosis after femoral neck fracture: a prospective study.Int Orthop. 2015 Jul;39(7):1417-22. doi: 10.1007/s00264-015-2709-7. Epub 2015 Feb 25. Int Orthop. 2015. PMID: 25711398
-
SPECT/CT in the Evaluation of Suspected Skeletal Pathology.Tomography. 2021 Oct 11;7(4):581-605. doi: 10.3390/tomography7040050. Tomography. 2021. PMID: 34698290 Free PMC article. Review.
-
Quantitative Characterization of Bone Viability of Femoral Head and Subchondral Bone by Using Single Photon Emission Computerized Tomography/Computerized Tomography (SPECT/CT).Med Sci Monit. 2020 May 20;26:e922624. doi: 10.12659/MSM.922624. Med Sci Monit. 2020. PMID: 32430492 Free PMC article.
-
Unusual Focal Lung Uptake without CT Abnormality on a Bone Scan: What Might It Mean?Diagnostics (Basel). 2022 Apr 8;12(4):934. doi: 10.3390/diagnostics12040934. Diagnostics (Basel). 2022. PMID: 35453982 Free PMC article.
-
Extra-osseous 99mTc methylene diphosphonate uptake detected enlargement of the knee joint in patient with polyarthritis.SAGE Open Med Case Rep. 2017 Nov 14;5:2050313X17741824. doi: 10.1177/2050313X17741824. eCollection 2017. SAGE Open Med Case Rep. 2017. PMID: 29163955 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical