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Editorial
. 2013 Jul;20(7):850-1.
doi: 10.1038/cdd.2013.43.

Autophagy protects from liver injury

Z He, H U Simon
Editorial

Autophagy protects from liver injury

Z He et al. Cell Death Differ. 2013 Jul.
No abstract available

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Figures

Figure 1
Figure 1
Autophagy overlaps with the extrinsic apoptosis pathway in liver cells. Deficient autophagy results in overactivation of JNK, which increases caspase-8 activation and allows the induction of TNF-dependent apoptosis. How autophagy regulates JNK activity remains still unknown. In addition, several canonical pro-apoptotic molecules, such as caspase-8, can be degraded by autophagy
See this image and copyright information in PMC

Comment on

References

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