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. 2013 Aug;10(8):495-500.
doi: 10.1038/nrgastro.2013.96. Epub 2013 Jun 11.

Helicobacter pylori research: historical insights and future directions

Kwong Ming Fock  1 , David Y Graham, Peter Malfertheiner
Affiliations

Helicobacter pylori research: historical insights and future directions

Kwong Ming Fock et al. Nat Rev Gastroenterol Hepatol. 2013 Aug.

Abstract

Helicobacter pylori leads to chronic gastritis, peptic ulcer disease and gastric cancer. With increasing issues of antibiotic resistance and changing epidemiology of this pathogen, new approaches are needed for effective management. In 1984, Dr Barry Marshall and Dr Robin Warren reported the association of Helicobacter pylori with peptic ulcers in The Lancet--a discovery that earned them the Nobel prize in Physiology or Medicine in 2005--but what progress have we made since then? Here, we have invited three international experts to give their insights into the advances in H. pylori research over the past 30 years and where research should be focused in the future.

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Conflict of interest statement

Competing interests

K. M. Fock declares no competing interests. D. Y. Graham declares associations with the following companies and organizations: Baylor College of Medicine, Novartis, Otsuka Pharmaceuticals and RedHill Biopharma. P. Malfertheiner declares associations with the following companies and organizations: AstraZeneca, Falk Foundation and Takeda. See the article online for details of these relationships.

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